What is the answer to the NYT Crossword clue "___ best friend" from October 22, 2025?

Crossword clue

“___ best friend”

This clue appeared as 59-Across in the NYT Crossword on Wednesday, October 22, 2025. The answer has 4 letters.

Answer · 4 lettersFirst appearance

MANS

Letters4

Starts withM

Ends withS

Vowels1

Where this clue has appeared

NYT Crossword
Oct 22, 20254 letters→

About this clue

The clue “___ best friend” ran in the NYT Crossword on October 22, 2025 as 59-Across. Its answer is a 4-letter word that starts with M and ends with S.

See every answer from the puzzle on the NYT Crossword page for October 22, 2025, or learn how clues like this work in our guide to crossword clue types.

More clues from this puzzle

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FAQ

What is the answer to the “___ best friend” clue?+

The answer is MANS (4 letters), from the NYT Crossword of October 22, 2025.

Where has this clue appeared?+

We have seen it 1 time in the NYT Crossword.

How do I find other NYT Crossword answers?+

Open the full list of answers for October 22, 2025, or browse every date on the NYT Crossword hub.